Adaptive immune resistance in HPV-associated head and neck squamous cell carcinoma
Human papillomavirus (HPV) types associated with head and neck cancer generally induce a robust immune response. Despite the establishment of such an inflammatory microenvironment, HPV is able to persist and promote malignant transformation. The PD-1:PD-L1 immune checkpoint may play a critical role...
Main Author: | |
---|---|
Format: | Online |
Language: | English |
Published: |
Landes Bioscience
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667901/ |