Rac1 Selective Activation Improves Retina Ganglion Cell Survival and Regeneration

In adult mammals, after optic nerve injury, retinal ganglion cells (RGCs) do not regenerate their axons and most of them die by apoptosis within a few days. Recently, several strategies that activate neuronal intracellular pathways were proposed to prevent such degenerative processes. The rho-relate...

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Bibliographic Details
Main Authors: Lorenzetto, Erika, Ettorre, Michele, Pontelli, Valeria, Bolomini-Vittori, Matteo, Bolognin, Silvia, Zorzan, Simone, Laudanna, Carlo, Buffelli, Mario
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667179/