Electrostatic Mis-Interactions Cause Overexpression Toxicity of Proteins in E. coli

A majority of E. coli proteins when overexpressed inhibit its growth, but the reasons behind overexpression toxicity of proteins remain unknown. Understanding the mechanism of overexpression toxicity is important from evolutionary, biotechnological and possibly clinical perspectives. Here we study s...

Full description

Bibliographic Details
Main Authors: Singh, Gajinder Pal, Dash, Debasis
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667126/