Clonal Expansion within Pneumococcal Serotype 6C after Use of Seven-Valent Vaccine

Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children. Within three years of PCV7 introduction, we observed a fourfold increase in serotype 6C carriage, pre...

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Bibliographic Details
Main Authors: Loman, Nicholas J., Gladstone, Rebecca A., Constantinidou, Chrystala, Tocheva, Anna S., Jefferies, Johanna M. C., Faust, Saul N., O’Connor, Leigh, Chan, Jacqueline, Pallen, Mark J., Clarke, Stuart C.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665553/