Potassium-Chloride Cotransporter 3 Interacts with Vav2 to Synchronize the Cell Volume Decrease Response with Cell Protrusion Dynamics

Loss-of-function of the potassium-chloride cotransporter 3 (KCC3) causes hereditary motor and sensory neuropathy with agenesis of the corpus callosum (HMSN/ACC), a severe neurodegenerative disease associated with defective midline crossing of commissural axons in the brain. Conversely, KCC3 over-exp...

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Bibliographic Details
Main Authors: Salin-Cantegrel, Adèle, Shekarabi, Masoud, Rasheed, Sarah, Charron, François M., Laganière, Janet, Gaudet, Rebecca, Dion, Patrick A., Lapointe, Jean-Yves, Rouleau, Guy A.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665532/