Association between melanocytic neoplasms and seborrheic keratosis: more than a coincidental collision?

Clinical observations and an expanding knowledge of cell-to-cell communication have led us to speculate that the finding of a melanocytic nevus in conjunction with a seborrheic keratosis is more than a coincidental collision of two lesions. Here we present five cases demonstrating dermoscopic featur...

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Bibliographic Details
Main Authors: DeFazio, Jennifer, Zalaudek, Iris, Busam, Klaus J., Cota, Carlo, Marghoob, Ashfaq
Format: Online
Language:English
Published: Derm101.com 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663343/
Description
Summary:Clinical observations and an expanding knowledge of cell-to-cell communication have led us to speculate that the finding of a melanocytic nevus in conjunction with a seborrheic keratosis is more than a coincidental collision of two lesions. Here we present five cases demonstrating dermoscopic features of both melanocytic lesions and seborrheic keratoses with corresponding histology. Four cases demonstrate dermoscopic features of a melanocytic nevus and seborrheic keratosis, and the final case a melanoma arising in association with a seborrheic keratosis.