Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine-mediated regulation of Tiam1

Exposure to psychostimulants results in structural and synaptic plasticity in striatal medium spiny neurons (MSNs). These cellular adaptations arise from alterations in genes that are highly implicated in the rearrangement of the actin-cytoskeleton, such as T-lymphoma invasion and metastasis 1 (Tiam...

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Main Authors: Chandra, Ramesh, Lenz, Jeffrey D., Gancarz, Amy M., Chaudhury, Dipesh, Schroeder, Gabrielle L., Han, Ming-Hu, Cheer, Joseph F., Dietz, David M., Lobo, Mary Kay
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662885/