The Type 2 Diabetes–Associated Gene Ide Is Required for Insulin Secretion and Suppression of α-Synuclein Levels in β-Cells

The Type 2 Diabetes–Associated Gene Ide Is Required for Insulin Secretion and Suppression of α-Synuclein Levels in β-Cells

Genome-wide association studies have identified several type 2 diabetes (T2D) risk loci linked to impaired β-cell function. The identity and function of the causal genes in these susceptibility loci remain, however, elusive. The HHEX/IDE T2D locus is associated with decreased insulin secretion in re...

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Bibliographic Details
Main Authors: Steneberg, Pär, Bernardo, Lisandro, Edfalk, Sara, Lundberg, Lisa, Backlund, Fredrik, Östenson, Claes-Göran, Edlund, Helena
Format: Online
Language:English
Published: American Diabetes Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661649/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661649/

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