Rapid Countermeasure Discovery against Francisella tularensis Based on a Metabolic Network Reconstruction

In the future, we may be faced with the need to provide treatment for an emergent biological threat against which existing vaccines and drugs have limited efficacy or availability. To prepare for this eventuality, our objective was to use a metabolic network-based approach to rapidly identify potent...

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Bibliographic Details
Main Authors: Chaudhury, Sidhartha, Abdulhameed, Mohamed Diwan M., Singh, Narender, Tawa, Gregory J., D’haeseleer, Patrik M., Zemla, Adam T., Navid, Ali, Zhou, Carol E., Franklin, Matthew C., Cheung, Jonah, Rudolph, Michael J., Love, James, Graf, John F., Rozak, David A., Dankmeyer, Jennifer L., Amemiya, Kei, Daefler, Simon, Wallqvist, Anders
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660459/