Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma

Determining the mechanism of treatment failure of VEGF signaling inhibitors for malignant glioma patients would provide insight into approaches to overcome therapeutic resistance. In this study, we demonstrate that human glioblastoma tumors failing bevacizumab have an increase in the mean percentage...

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Bibliographic Details
Main Authors: de Groot, John, Liang, Ji, Kong, Ling-Yuan, Wei, Jun, Piao, Yuji, Fuller, Gregory, Qiao, Wei, Heimberger, Amy B.
Format: Online
Language:English
Published: Impact Journals LLC 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660053/