Inhibitory effects of total saponin from Korean red ginseng via vasodilator-stimulated phosphoprotein-Ser157 phosphorylation on thrombin-induced platelet aggregation

In this study, we have investigated the effects of total saponin from Korean red ginseng (TSKRG) on thrombin-induced platelet aggregation. TSKRG dose-dependently inhibited thrombin-induced platelet aggregation with IC50 value of about 81.1 μg/mL. In addition, TSKRG dose-dependently decreased thrombi...

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Bibliographic Details
Main Authors: Lee, Dong-Ha, Cho, Hyun-Jeong, Kim, Hyun-Hong, Rhee, Man Hee, Ryu, Jin-Hyeob, Park, Hwa-Jin
Format: Online
Language:English
Published: The Korean Society of Ginseng 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659637/