Ginsenoside Rp1, a Ginsenoside Derivative, Blocks Promoter Activation of iNOS and COX-2 Genes by Suppression of an IKKβ-mediated NF-кB Pathway in HEK293 Cells

Ginsenoside (G) Rp1 is a ginseng saponin derivative with anti-cancer and anti-inflammatory activities. In this study, we examined the mechanism by which G-Rp1 inhibits inflammatory responses of cells. We did this using a strategy in which DNA constructs containing cyclooxygenase (COX)-2 and inducibl...

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Bibliographic Details
Main Authors: Shen, Ting, Lee, Jaehwi, Park, Myung Hwan, Lee, Yong Gyu, Rho, Ho Sik, Kwak, Yi-Seong, Rhee, Man Hee, Park, Yung Chul, Cho, Jae Youl
Format: Online
Language:English
Published: The Korean Society of Ginseng 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659523/