Tumor Cell Clone Expressing the Membrane-bound Form of IL-12p35 Subunit Stimulates Antitumor Immune Responses Dominated by CD8+ T Cells
IL-12 is a secretory heterodimeric cytokine composed of p35 and p40 subunits. IL-12 p35 and p40 subunits are sometimes produced as monomers or homodimers. IL-12 is also produced as a membrane-bound form in some cases. In this study, we hypothesized that the membrane-bound form of IL-12 subunits may...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Association of Immunologists
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659257/ |