The Impact of a Ligand Binding on Strand Migration in the SAM-I Riboswitch

Riboswitches sense cellular concentrations of small molecules and use this information to adjust synthesis rates of related metabolites. Riboswitches include an aptamer domain to detect the ligand and an expression platform to control gene expression. Previous structural studies of riboswitches larg...

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Bibliographic Details
Main Authors: Huang, Wei, Kim, Joohyun, Jha, Shantenu, Aboul-ela, Fareed
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656099/