Comparison of MicroRNA Deep Sequencing of Matched Formalin-Fixed Paraffin-Embedded and Fresh Frozen Cancer Tissues

MicroRNAs regulate several aspects of tumorigenesis and cancer progression. Most cancer tissues are archived formalin-fixed and paraffin-embedded (FFPE). While microRNAs are a more stable form of RNA thought to withstand FFPE-processing and degradation there is only limited evidence for the latter a...

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Bibliographic Details
Main Authors: Meng, Wei, McElroy, Joseph P., Volinia, Stefano, Palatini, Jeff, Warner, Sarah, Ayers, Leona W., Palanichamy, Kamalakannan, Chakravarti, Arnab, Lautenschlaeger, Tim
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655971/