Malonate Inhibits Virulence Gene Expression in Vibrio cholerae

We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae. In this study, we found that the addition of malonate, an inhibitor of succinate dehydrogenase (SDH), decreased toxT transcription in V. cholerae, a...

Full description

Bibliographic Details
Main Authors: Minato, Yusuke, Fassio, Sara R., Häse, Claudia C.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652848/