Eosinophils in Chronic Urticaria: Supporting or Leading Actors?
Although their number may be increased in skin lesions, eosinophils have been rather neglected as possible participants to the pathogenesis of chronic urticaria because of the absence of peripheral eosinophilia in patients with this disease. However, recent data suggest a potentially relevant role p...
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| Format: | Online |
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World Allergy Organization
2009
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651011/ |
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pubmed-36510112013-07-12 Eosinophils in Chronic Urticaria: Supporting or Leading Actors? Asero, Riccardo Cugno, Massimo Tedeschi, Alberto Reviews Although their number may be increased in skin lesions, eosinophils have been rather neglected as possible participants to the pathogenesis of chronic urticaria because of the absence of peripheral eosinophilia in patients with this disease. However, recent data suggest a potentially relevant role played by activated eosinophils both in triggering the tissue factor pathway of coagulation cascade and as a source of vascular endothelial growth factor. Such phenomena seem more pronounced in patients showing a more severe disease. The present study will rediscuss the potential role of this cell line in chronic urticaria in the light of these recent observations. World Allergy Organization 2009-09-15 /pmc/articles/PMC3651011/ /pubmed/23283151 http://dx.doi.org/10.1097/WOX.0b013e3181bb965f Text en Copyright ©2009 World Allergy Organization; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Asero, Riccardo Cugno, Massimo Tedeschi, Alberto |
| spellingShingle |
Asero, Riccardo Cugno, Massimo Tedeschi, Alberto Eosinophils in Chronic Urticaria: Supporting or Leading Actors? |
| author_facet |
Asero, Riccardo Cugno, Massimo Tedeschi, Alberto |
| author_sort |
Asero, Riccardo |
| title |
Eosinophils in Chronic Urticaria: Supporting or Leading Actors? |
| title_short |
Eosinophils in Chronic Urticaria: Supporting or Leading Actors? |
| title_full |
Eosinophils in Chronic Urticaria: Supporting or Leading Actors? |
| title_fullStr |
Eosinophils in Chronic Urticaria: Supporting or Leading Actors? |
| title_full_unstemmed |
Eosinophils in Chronic Urticaria: Supporting or Leading Actors? |
| title_sort |
eosinophils in chronic urticaria: supporting or leading actors? |
| description |
Although their number may be increased in skin lesions, eosinophils have been rather neglected as possible participants to the pathogenesis of chronic urticaria because of the absence of peripheral eosinophilia in patients with this disease. However, recent data suggest a potentially relevant role played by activated eosinophils both in triggering the tissue factor pathway of coagulation cascade and as a source of vascular endothelial growth factor. Such phenomena seem more pronounced in patients showing a more severe disease. The present study will rediscuss the potential role of this cell line in chronic urticaria in the light of these recent observations. |
| publisher |
World Allergy Organization |
| publishDate |
2009 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651011/ |
| _version_ |
1611976936621342720 |