The spatial pattern of light determines the kinetics and modulates backpropagation of optogenetic action potentials

Optogenetics offers an unprecedented ability to spatially target neuronal stimulations. This study investigated via simulation, for the first time, how the spatial pattern of excitation affects the response of channelrhodopsin-2 (ChR2) expressing neurons. First we described a methodology for modelin...

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Bibliographic Details
Main Authors: Grossman, Nir, Simiaki, Vasiliki, Martinet, Claire, Toumazou, Christofer, Schultz, Simon R., Nikolic, Konstantin
Format: Online
Language:English
Published: Springer US 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650242/