Chromosome Movements Promoted by the Mitochondrial Protein SPD-3 Are Required for Homology Search during Caenorhabditis elegans Meiosis

Pairing of homologous chromosomes during early meiosis is essential to prevent the formation of aneuploid gametes. Chromosome pairing includes a step of homology search followed by the stabilization of homolog interactions by the synaptonemal complex (SC). These events coincide with dramatic changes...

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Bibliographic Details
Main Authors: Labrador, Leticia, Barroso, Consuelo, Lightfoot, James, Müller-Reichert, Thomas, Flibotte, Stephane, Taylor, Jon, Moerman, Donald G., Villeneuve, Anne M., Martinez-Perez, Enrique
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649994/