Epigenetic Silencing of DKK3 in Medulloblastoma

Medulloblastoma (MB) is a malignant pediatric brain tumor arising in the cerebellum consisting of four distinct subgroups: WNT, SHH, Group 3 and Group 4, which exhibit different molecular phenotypes. We studied the expression of Dickkopf (DKK) 1–4 family genes, inhibitors of the Wnt signaling cascad...

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Bibliographic Details
Main Authors: Valdora, Francesca, Banelli, Barbara, Stigliani, Sara, Pfister, Stefan M., Moretti, Stefano, Kool, Marcel, Remke, Marc, Bai, Alfa H.C., Brigati, Claudio, Hielscher, Thomas, Romani, Massimo, Servidei, Tiziana, Zollo, Massimo, Cinalli, Giuseppe, Oberthuer, André, Tonini, Gian Paolo, Coco, Simona
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645699/