Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells
The zwitterionic capsular polysaccharide A (PSA) of Bacteroides fragilis is the first carbohydrate antigen described to be presented in major histocompatibility complex (MHC) class II for the induction of CD4+ T cell responses. However, the identity of the receptor mediating binding and internalizat...
Main Authors: | Bloem, Karien, García-Vallejo, Juan J., Vuist, Ilona M., Cobb, Brian A., van Vliet, Sandra J., van Kooyk, Yvette |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644800/ |
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