Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA delivery

Cell-penetrating peptides are widely used as molecular transporters for the internalization inside cells of various cargo, including proteins and nucleic acids. A special role is played by arginine-rich peptides and oligoarginines covalently linked or simply mixed with the cargo. Here we report cell...

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Bibliographic Details
Main Authors: Bagnacani, Valentina, Franceschi, Valentina, Bassi, Michele, Lomazzi, Michela, Donofrio, Gaetano, Sansone, Francesco, Casnati, Alessandro, Ungaro, Rocco
Format: Online
Language:English
Published: Nature Pub. Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644092/