Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement

Langerhans cell histiocytosis (LCH) is a rare disease affecting predominantly children. The course of the disease varies, from spontaneous resolution to a progressive multisystem disorder with organ dysfunction and potential life-threatening complications. Diagnosis of LCH is often difficult and may...

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Main Authors:	Chandekar, Sushama A, Shah, Vinaya B, Kavishwar, Vikas
Format:	Online
Language:	English
Published:	Medknow Publications & Media Pvt Ltd 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643374/

id	pubmed-3643374
recordtype	oai_dc
spelling	pubmed-36433742013-05-09 Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement Chandekar, Sushama A Shah, Vinaya B Kavishwar, Vikas Case Report Langerhans cell histiocytosis (LCH) is a rare disease affecting predominantly children. The course of the disease varies, from spontaneous resolution to a progressive multisystem disorder with organ dysfunction and potential life-threatening complications. Diagnosis of LCH is often difficult and may be delayed because of its rarity and especially so if it occurs with unusual presentation. Fine needle aspiration cytology of a 4 year old male child, a case of LCH is presented with a purpose of highlighting the characteristic cytological features. A high index of suspicion, awareness of characteristic cytological features of LCH and its differential diagnoses is necessary. This can obviate the need of biopsy and electron microscopy. Immunohistochemistry if available can be performed on cytology smear and cell block. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3643374/ /pubmed/23661952 http://dx.doi.org/10.4103/0970-9371.107533 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Chandekar, Sushama A Shah, Vinaya B Kavishwar, Vikas
spellingShingle	Chandekar, Sushama A Shah, Vinaya B Kavishwar, Vikas Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement
author_facet	Chandekar, Sushama A Shah, Vinaya B Kavishwar, Vikas
author_sort	Chandekar, Sushama A
title	Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement
title_short	Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement
title_full	Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement
title_fullStr	Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement
title_full_unstemmed	Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement
title_sort	cytological diagnosis of langerhans cell histiocytosis with cutaneous involvement
description	Langerhans cell histiocytosis (LCH) is a rare disease affecting predominantly children. The course of the disease varies, from spontaneous resolution to a progressive multisystem disorder with organ dysfunction and potential life-threatening complications. Diagnosis of LCH is often difficult and may be delayed because of its rarity and especially so if it occurs with unusual presentation. Fine needle aspiration cytology of a 4 year old male child, a case of LCH is presented with a purpose of highlighting the characteristic cytological features. A high index of suspicion, awareness of characteristic cytological features of LCH and its differential diagnoses is necessary. This can obviate the need of biopsy and electron microscopy. Immunohistochemistry if available can be performed on cytology smear and cell block.
publisher	Medknow Publications & Media Pvt Ltd
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3643374/
_version_	1611974927012855808

Cytological diagnosis of Langerhans cell histiocytosis with cutaneous involvement

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