Architecture of the Pol III–clamp–exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair

Architecture of the Pol III–clamp–exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair

Chemical crosslinking coupled with mass spectrometry to structurally map the core bacterial replicase reveals the proofreading subunit to modulate DNA clamp interactions with the catalytic subunit and alternative translesion synthesis polymerases.

Bibliographic Details
Main Authors: Toste Rêgo, Ana, Holding, Andrew N, Kent, Helen, Lamers, Meindert H
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642679/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642679/

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