BRAF, GNAQ, and GNA11 mutations and copy number in pediatric low-grade glioma

BRAF, GNAQ, and GNA11 mutations and copy number in pediatric low-grade glioma

► We investigated the occurrence of BRAF, GNAQ, and GNA11 mutations in pediatric low-grade glioma. ► We found an increase in the copy number of BRAF. ► BRAF and GNAQ mutations are mutually exclusive. ► Understanding the molecular basis of low-grade glioma may increase treatment options.

Bibliographic Details
Main Authors: Laviv, Yosef, Toledano, Helen, Michowiz, Shalom, Dratviman-Storobinsky, Olga, Turm, Yuval, Fichman-Horn, Suzana, Kagnovski, Ella, Goldenberg-Cohen, Nitza
Format: Online
Language:English
Published: Elsevier 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642131/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642131/

Similar Items