Partial Agonism of Taurine at Gamma-Containing Native and Recombinant GABAA Receptors

Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissues which regulates osmolarity, ion channel activity and glucose homeostasis. The structural requirements of GABAA-receptors (GABAAR) gated by taurine are not yet known. We determined taurine potency a...

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Bibliographic Details
Main Authors: Kletke, Olaf, Gisselmann, Guenter, May, Andrea, Hatt, Hanns, A. Sergeeva, Olga
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640040/