Characterization of the melanoma brain metastatic niche in mice and humans

Brain metastases occur in 15% of patients with melanoma and are associated with a dismal prognosis. Here, we investigate the architectural phenotype and stromal reaction of melanoma brain metastasis in mice and humans. A syngeneic, green fluorescence protein (GFP)-expressing murine B16-F1 melanoma c...

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Bibliographic Details
Main Authors: Amit, Moran, Laider-Trejo, Leonor, Shalom, Vardit, Shabtay-Orbach, Ayelet, Krelin, Yakov, Gil, Ziv
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639654/