Exploratory Bioinformatics Study of lncRNAs in Alzheimer's Disease mRNA Sequences with Application to Drug Development

Exploratory Bioinformatics Study of lncRNAs in Alzheimer's Disease mRNA Sequences with Application to Drug Development

Long noncoding RNA (lncRNA) within mRNA sequences of Alzheimer's disease genes, namely, APP, APOE, PSEN1, and PSEN2, has been analyzed using fractal dimension (FD) computation and correlation analysis. We examined lncRNA by comparing mRNA FD to corresponding coding DNA sequences (CDSs) FD. APP,...

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Bibliographic Details
Main Authors: Holden, T., Nguyen, A., Lin, E., Cheung, E., Dehipawala, S., Ye, J., Tremberger, G., Lieberman, D., Cheung, T.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639631/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639631/

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