Sulforaphane Attenuates Gentamicin-Induced Nephrotoxicity: Role of Mitochondrial Protection

Sulforaphane (SFN), an isothiocyanate naturally occurring in Cruciferae, induces cytoprotection in several tissues. Its protective effect has been associated with its ability to induce cytoprotective enzymes through an Nrf2-dependent pathway. Gentamicin (GM) is a widely used antibiotic; nephrotoxici...

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Bibliographic Details
Main Authors: Negrette-Guzmán, Mario, Huerta-Yepez, Sara, Medina-Campos, Omar Noel, Zatarain-Barrón, Zyanya Lucía, Hernández-Pando, Rogelio, Torres, Ismael, Tapia, Edilia, Pedraza-Chaverri, José
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638608/