Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome

The phenomenon that the same syndrome turns up in different diseases appears in the sight of people around the world, which raises the thought for possibility of “Same Treatment for Different Diseases.” Actually, treatment based on ZHENG classification in Traditional Chinese Medicine could bring rev...

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Main Authors:	Dai, Jianye, Sun, Shujun, Cao, Jianmei, Zhao, Yu, Cao, Huijuan, Zheng, Ningning, Fang, Junwei, Wang, Yang, Zhang, Wei, Zhang, Yongyu, Hu, Yiyang, Cao, Zhiwei
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638589/

id	pubmed-3638589
recordtype	oai_dc
spelling	pubmed-36385892013-05-20 Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome Dai, Jianye Sun, Shujun Cao, Jianmei Zhao, Yu Cao, Huijuan Zheng, Ningning Fang, Junwei Wang, Yang Zhang, Wei Zhang, Yongyu Hu, Yiyang Cao, Zhiwei Research Article The phenomenon that the same syndrome turns up in different diseases appears in the sight of people around the world, which raises the thought for possibility of “Same Treatment for Different Diseases.” Actually, treatment based on ZHENG classification in Traditional Chinese Medicine could bring revelation for the former finding. The dampness-heat syndrome in chronic hepatitis B and nonalcoholic fatty liver is regarded as the breakthrough point. We discussed the molecular mechanism of similar connotation that exists in chronic hepatitis B and nonalcoholic fatty liver by metabonomics to give the modern understanding of dampness-heat syndrome. Both urine and serum metabolic profiling revealed that obvious differences existed between dampness-heat syndrome and non-dampness-heat syndrome but the commonality was proved to appear in chronic hepatitis B and nonalcoholic fatty liver patients with dampness-heat syndrome. Furthermore, disorder of body fluid metabolism, decline in digestive capacity, and imbalance of intestinal flora were found to be the new guiding for treatment, with the hope to provide the basis for Chinese personalized medicine. Hindawi Publishing Corporation 2013 2013-04-08 /pmc/articles/PMC3638589/ /pubmed/23690853 http://dx.doi.org/10.1155/2013/793820 Text en Copyright © 2013 Jianye Dai et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Dai, Jianye Sun, Shujun Cao, Jianmei Zhao, Yu Cao, Huijuan Zheng, Ningning Fang, Junwei Wang, Yang Zhang, Wei Zhang, Yongyu Hu, Yiyang Cao, Zhiwei
spellingShingle	Dai, Jianye Sun, Shujun Cao, Jianmei Zhao, Yu Cao, Huijuan Zheng, Ningning Fang, Junwei Wang, Yang Zhang, Wei Zhang, Yongyu Hu, Yiyang Cao, Zhiwei Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome
author_facet	Dai, Jianye Sun, Shujun Cao, Jianmei Zhao, Yu Cao, Huijuan Zheng, Ningning Fang, Junwei Wang, Yang Zhang, Wei Zhang, Yongyu Hu, Yiyang Cao, Zhiwei
author_sort	Dai, Jianye
title	Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome
title_short	Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome
title_full	Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome
title_fullStr	Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome
title_full_unstemmed	Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome
title_sort	similar connotation in chronic hepatitis b and nonalcoholic fatty liver patients with dampness-heat syndrome
description	The phenomenon that the same syndrome turns up in different diseases appears in the sight of people around the world, which raises the thought for possibility of “Same Treatment for Different Diseases.” Actually, treatment based on ZHENG classification in Traditional Chinese Medicine could bring revelation for the former finding. The dampness-heat syndrome in chronic hepatitis B and nonalcoholic fatty liver is regarded as the breakthrough point. We discussed the molecular mechanism of similar connotation that exists in chronic hepatitis B and nonalcoholic fatty liver by metabonomics to give the modern understanding of dampness-heat syndrome. Both urine and serum metabolic profiling revealed that obvious differences existed between dampness-heat syndrome and non-dampness-heat syndrome but the commonality was proved to appear in chronic hepatitis B and nonalcoholic fatty liver patients with dampness-heat syndrome. Furthermore, disorder of body fluid metabolism, decline in digestive capacity, and imbalance of intestinal flora were found to be the new guiding for treatment, with the hope to provide the basis for Chinese personalized medicine.
publisher	Hindawi Publishing Corporation
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638589/
_version_	1611973410358820864

Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome

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