High-Resolution Mapping of H1 Linker Histone Variants in Embryonic Stem Cells

H1 linker histones facilitate higher-order chromatin folding and are essential for mammalian development. To achieve high-resolution mapping of H1 variants H1d and H1c in embryonic stem cells (ESCs), we have established a knock-in system and shown that the N-terminally tagged H1 proteins are functio...

Full description

Bibliographic Details
Main Authors: Cao, Kaixiang, Lailler, Nathalie, Zhang, Yunzhe, Kumar, Ashwath, Uppal, Karan, Liu, Zheng, Lee, Eva K., Wu, Hongwei, Medrzycki, Magdalena, Pan, Chenyi, Ho, Po-Yi, Cooper, Guy P., Dong, Xiao, Bock, Christoph, Bouhassira, Eric E., Fan, Yuhong
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636266/