Selective selC-Independent Selenocysteine Incorporation into Formate Dehydrogenases

The formate dehydrogenases (Fdh) Fdh-O, Fdh-N, and Fdh-H, are the only proteins in Escherichia coli that incorporate selenocysteine at a specific position by decoding a UGA codon. However, an excess of selenium can lead to toxicity through misincorporation of selenocysteine into proteins. To determi...

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Bibliographic Details
Main Authors: Zorn, Michael, Ihling, Christian H., Golbik, Ralph, Sawers, R. Gary, Sinz, Andrea
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636253/