Granulysin-Bearing Cells in the Skin Lesions of Acute Graft-versus-Host Disease: Possible Mechanisms for Hypohidrosis in Graft-versus-Host Disease

Graft-versus-host disease (GVHD) is an important complication of bone marrow transplantation and is known to induce sweat gland abnormalities. We employed immunohistochemical staining for granulysin, dermcidin as well as IL-17 and Foxp3 in the lesional skin of 7 patients with acute GVHD. Granulysin-...

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Bibliographic Details
Main Authors: Furudate, Sadanori, Fujimura, Taku, Kambayashi, Yumi, Aiba, Setsuya
Format: Online
Language:English
Published: S. Karger AG 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635966/