Risk of Generalized Vitiligo is Associated with the Common 55R-94A-247H Variant Haplotype of GZMB (Encoding Granzyme B)
Generalized vitiligo (GV) is characterized by autoimmune destruction of melanocytes by skin-homing cytotoxic T-cells (CTLs) that target melanocyte autoantigens. Two recent genomewide association studies (GWAS) of GV in European-derived whites (EUR) have demonstrated genetic association with GZMB, en...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634907/ |