Structure-Based Search for New Inhibitors of Cholinesterases

Cholinesterases are important biological targets responsible for regulation of cholinergic transmission, and their inhibitors are used for the treatment of Alzheimer’s disease. To design new cholinesterase inhibitors, of different structure-based design strategies was followed, including the modific...

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Bibliographic Details
Main Authors: Bajda, Marek, Więckowska, Anna, Hebda, Michalina, Guzior, Natalia, Sotriffer, Christoph A., Malawska, Barbara
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634507/