Impact of Diffusion Barriers to Small Cytotoxic Molecules on the Efficacy of Immunotherapy in Breast Cancer

Impact of Diffusion Barriers to Small Cytotoxic Molecules on the Efficacy of Immunotherapy in Breast Cancer

Molecular-focused cancer therapies, e.g., molecularly targeted therapy and immunotherapy, so far demonstrate only limited efficacy in cancer patients. We hypothesize that underestimating the role of biophysical factors that impact the delivery of drugs or cytotoxic cells to the target sites (for ass...

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Bibliographic Details
Main Authors: Das, Hiranmoy, Wang, Zhihui, Niazi, M. Khalid Khan, Aggarwal, Reeva, Lu, Jingwei, Kanji, Suman, Das, Manjusri, Joseph, Matthew, Gurcan, Metin, Cristini, Vittorio
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631240/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631240/

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