Population Pharmacokinetics of Intramuscular Artesunate in African Children With Severe Malaria: Implications for a Practical Dosing Regimen

Parenteral artesunate (ARS) is the drug of choice for the treatment of severe malaria. Pharmacokinetics data on intramuscular ARS are limited with respect to the main treatment group that carries the highest mortality, namely, critically ill children with severe malaria. A population pharmacokinetic...

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Bibliographic Details
Main Authors: Hendriksen, ICE, Mtove, G, Kent, A, Gesase, S, Reyburn, H, Lemnge, M M, Lindegardh, N, Day, N P J, von Seidlein, L, White, N J, Dondorp, A M, Tarning, J
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630454/