A nonviral pHEMA+chitosan nanosphere-mediated high-efficiency gene delivery system

The transport of DNA into eukaryotic cells is minimal because of the cell membrane barrier, and this limits the application of DNA vaccines, gene silencing, and gene therapy. Several available transfection reagents and techniques have been used to circumvent this problem. Alternatively, nonviral nan...

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Bibliographic Details
Main Authors: Eroglu, Erdal, Tiwari, Pooja M, Waffo, Alain B, Miller, Michael E, Vig, Komal, Dennis, Vida A, Singh, Shree R
Format: Online
Language:English
Published: Dove Medical Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629879/