Temporal Trends of HLA, CTLA-4 and PTPN22 Genotype Frequencies among Type 1 Diabetes in Continental Italy

The incidence of type 1 diabetes has, progressively, increased worldwide over the last decades and also in Continental Italian population. Previous studies performed in northern European countries, showed, alongside a general increase in the disease incidence, a decreasing frequency of the highest r...

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Bibliographic Details
Main Authors: Spoletini, Marialuisa, Zampetti, Simona, Campagna, Giuseppe, Marandola, Lidia, Capizzi, Marco, Buzzetti, Raffaella
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629148/