Hypermethylation and Post-Transcriptional Regulation of DNA Methyltransferases in the Ovarian Carcinomas of the Laying Hen

DNA methyltransferases (DNMTs) are key regulators of DNA methylation and have crucial roles in carcinogenesis, embryogenesis and epigenetic modification. In general, DNMT1 has enzymatic activity affecting maintenance of DNA methylation, whereas DNMT3A and DNMT3B are involved in de novo methylation e...

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Bibliographic Details
Main Authors: Lee, Jin-Young, Jeong, Wooyoung, Lim, Whasun, Lim, Chul-Hong, Bae, Seung-Min, Kim, Jinyoung, Bazer, Fuller W., Song, Gwonhwa
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629126/