A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes

Rhinoscleroma is a human specific chronic disease characterized by the formation of granuloma in the airways, caused by the bacterium Klebsiella pneumoniae subspecies rhinoscleromatis, a species very closely related to K. pneumoniae subspecies pneumoniae. It is characterized by the appearance of spe...

Full description

Bibliographic Details
Main Authors: Fevre, Cindy, Almeida, Ana S, Taront, Solenne, Pedron, Thierry, Huerre, Michel, Prevost, Marie-Christine, Kieusseian, Aurélie, Cumano, Ana, Brisse, Sylvain, Sansonetti, Philippe J, Tournebize, Régis
Format: Online
Language:English
Published: WILEY-VCH Verlag 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628109/