Single-molecule chemical denaturation of riboswitches
To date, single-molecule RNA science has been developed almost exclusively around the effect of metal ions as folding promoters and stabilizers of the RNA structure. Here, we introduce a novel strategy that combines single-molecule Förster resonance energy transfer (FRET) and chemical denaturation t...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627600/ |