Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

This study aimed to evaluate the acute toxicity of intravenously administrated amorphous silica nanoparticles (SNPs) in mice. The lethal dose, 50 (LD50), of intravenously administrated SNPs was calculated in mice using Dixon's up-and-down method (262.45±33.78 mg/kg). The acute toxicity was eval...

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Bibliographic Details
Main Authors: Yu, Yang, Li, Yang, Wang, Wen, Jin, Minghua, Du, Zhongjun, Li, Yanbo, Duan, Junchao, Yu, Yongbo, Sun, Zhiwei
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625170/