Effectiveness of Heparin during Long-Term Tocolysis

Objective. Drip infusion during long-term tocolysis causes mechanical and infectious vasculitis and increases the frequency of peripheral venous catheter exchange (PVC), thereby placing a burden on patients. Our study aim is to confirm whether heparin ameliorates pain due to vasculitis during long-...

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Main Authors:	Inagaki, Tetsunori, Makino, Shintaro, Yorifuji, Takashi, Sugimura, Motoi, Takeda, Satoru
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622413/

id	pubmed-3622413
recordtype	oai_dc
spelling	pubmed-36224132013-04-15 Effectiveness of Heparin during Long-Term Tocolysis Inagaki, Tetsunori Makino, Shintaro Yorifuji, Takashi Sugimura, Motoi Takeda, Satoru Clinical Study Objective. Drip infusion during long-term tocolysis causes mechanical and infectious vasculitis and increases the frequency of peripheral venous catheter exchange (PVC), thereby placing a burden on patients. Our study aim is to confirm whether heparin ameliorates pain due to vasculitis during long-term tocolysis and reduces the frequency of peripheral venous catheter exchange. Design. Prospective study. Setting and Sample. All the patients requiring admission because of the presence of uterine contraction or progressive cervical dilatation from August 2009 to June 2011 at Juntendo University in Japan. Methods. Heparin was used for patients at the time the total number of peripheral venous catheter exchanges exceeded 5 in two weeks, and we evaluated whether heparin reduced the frequency of peripheral venous catheter exchange and improved the visual analog scale (VAS) for patients. The main outcome measures frequency of PVC exchange and VAS. Results. This study demonstrated that heparin reduced the frequency of peripheral venous catheter exchange (P = 0.0069) and VAS (P = 0.042). No side effects were noted. Conclusion. Heparin could satisfy patients during long-term tocolysis in terms of ameliorating pain due to vasculitis and reducing the PVC exchange frequency. Hindawi Publishing Corporation 2013-03-27 /pmc/articles/PMC3622413/ /pubmed/23589778 http://dx.doi.org/10.1155/2013/650532 Text en Copyright © 2013 Tetsunori Inagaki et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Inagaki, Tetsunori Makino, Shintaro Yorifuji, Takashi Sugimura, Motoi Takeda, Satoru
spellingShingle	Inagaki, Tetsunori Makino, Shintaro Yorifuji, Takashi Sugimura, Motoi Takeda, Satoru Effectiveness of Heparin during Long-Term Tocolysis
author_facet	Inagaki, Tetsunori Makino, Shintaro Yorifuji, Takashi Sugimura, Motoi Takeda, Satoru
author_sort	Inagaki, Tetsunori
title	Effectiveness of Heparin during Long-Term Tocolysis
title_short	Effectiveness of Heparin during Long-Term Tocolysis
title_full	Effectiveness of Heparin during Long-Term Tocolysis
title_fullStr	Effectiveness of Heparin during Long-Term Tocolysis
title_full_unstemmed	Effectiveness of Heparin during Long-Term Tocolysis
title_sort	effectiveness of heparin during long-term tocolysis
description	Objective. Drip infusion during long-term tocolysis causes mechanical and infectious vasculitis and increases the frequency of peripheral venous catheter exchange (PVC), thereby placing a burden on patients. Our study aim is to confirm whether heparin ameliorates pain due to vasculitis during long-term tocolysis and reduces the frequency of peripheral venous catheter exchange. Design. Prospective study. Setting and Sample. All the patients requiring admission because of the presence of uterine contraction or progressive cervical dilatation from August 2009 to June 2011 at Juntendo University in Japan. Methods. Heparin was used for patients at the time the total number of peripheral venous catheter exchanges exceeded 5 in two weeks, and we evaluated whether heparin reduced the frequency of peripheral venous catheter exchange and improved the visual analog scale (VAS) for patients. The main outcome measures frequency of PVC exchange and VAS. Results. This study demonstrated that heparin reduced the frequency of peripheral venous catheter exchange (P = 0.0069) and VAS (P = 0.042). No side effects were noted. Conclusion. Heparin could satisfy patients during long-term tocolysis in terms of ameliorating pain due to vasculitis and reducing the PVC exchange frequency.
publisher	Hindawi Publishing Corporation
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622413/
_version_	1611969242852229120

Effectiveness of Heparin during Long-Term Tocolysis

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