The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice
Cachexia, or muscle-wasting syndrome, is one of the major causes of death in patients affected by diseases such as cancer, AIDS and sepsis. However, no effective anti-cachectic treatment is currently available. Here we show that a low dose of pateamine A, an inhibitor of translation initiation, prev...
| Main Authors: | , , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Pub. Group
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621420/ |