Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia
Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. These changes include microvascular constriction, increased leukocyte-endothelial interactions, blood brain barrier disruption, and microthrombus formation. T...
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pubmed-36213722013-04-15 Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia Tso, Michael K. Macdonald, R. Loch Review Article Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. These changes include microvascular constriction, increased leukocyte-endothelial interactions, blood brain barrier disruption, and microthrombus formation. This paper will look at various animal and preclinical studies that investigate these various microvascular changes, perhaps providing insight in how these microvessels can be a therapeutic target in both subarachnoid hemorrhage and transient global cerebral ischemia. Hindawi Publishing Corporation 2013 2013-03-25 /pmc/articles/PMC3621372/ /pubmed/23589781 http://dx.doi.org/10.1155/2013/425281 Text en Copyright © 2013 M. K. Tso and R. L. Macdonald. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Tso, Michael K. Macdonald, R. Loch |
spellingShingle |
Tso, Michael K. Macdonald, R. Loch Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia |
author_facet |
Tso, Michael K. Macdonald, R. Loch |
author_sort |
Tso, Michael K. |
title |
Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia |
title_short |
Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia |
title_full |
Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia |
title_fullStr |
Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia |
title_full_unstemmed |
Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia |
title_sort |
acute microvascular changes after subarachnoid hemorrhage and transient global cerebral ischemia |
description |
Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. These changes include microvascular constriction, increased leukocyte-endothelial interactions, blood brain barrier disruption, and microthrombus formation. This paper will look at various animal and preclinical studies that investigate these various microvascular changes, perhaps providing insight in how these microvessels can be a therapeutic target in both subarachnoid hemorrhage and transient global cerebral ischemia. |
publisher |
Hindawi Publishing Corporation |
publishDate |
2013 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621372/ |
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1611968913389649920 |