Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia

Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. These changes include microvascular constriction, increased leukocyte-endothelial interactions, blood brain barrier disruption, and microthrombus formation. T...

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Main Authors: Tso, Michael K., Macdonald, R. Loch
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621372/
id pubmed-3621372
recordtype oai_dc
spelling pubmed-36213722013-04-15 Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia Tso, Michael K. Macdonald, R. Loch Review Article Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. These changes include microvascular constriction, increased leukocyte-endothelial interactions, blood brain barrier disruption, and microthrombus formation. This paper will look at various animal and preclinical studies that investigate these various microvascular changes, perhaps providing insight in how these microvessels can be a therapeutic target in both subarachnoid hemorrhage and transient global cerebral ischemia. Hindawi Publishing Corporation 2013 2013-03-25 /pmc/articles/PMC3621372/ /pubmed/23589781 http://dx.doi.org/10.1155/2013/425281 Text en Copyright © 2013 M. K. Tso and R. L. Macdonald. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Tso, Michael K.
Macdonald, R. Loch
spellingShingle Tso, Michael K.
Macdonald, R. Loch
Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia
author_facet Tso, Michael K.
Macdonald, R. Loch
author_sort Tso, Michael K.
title Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia
title_short Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia
title_full Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia
title_fullStr Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia
title_full_unstemmed Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia
title_sort acute microvascular changes after subarachnoid hemorrhage and transient global cerebral ischemia
description Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. These changes include microvascular constriction, increased leukocyte-endothelial interactions, blood brain barrier disruption, and microthrombus formation. This paper will look at various animal and preclinical studies that investigate these various microvascular changes, perhaps providing insight in how these microvessels can be a therapeutic target in both subarachnoid hemorrhage and transient global cerebral ischemia.
publisher Hindawi Publishing Corporation
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621372/
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