PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

PD-L1 decreases anti-viral CD8+ T cell motility and PD-1 blockade restores motility in the presence of high viral loads.

Bibliographic Details
Main Authors: Zinselmeyer, Bernd H., Heydari, Sara, Sacristán, Catarina, Nayak, Debasis, Cammer, Michael, Herz, Jasmin, Cheng, Xiaoxiao, Davis, Simon J., Dustin, Michael L., McGavern, Dorian B.
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620347/