Inhibition of the Receptor Tyrosine Kinase ROR1 by Anti-ROR1 Monoclonal Antibodies and siRNA Induced Apoptosis of Melanoma Cells

Inhibition of the Receptor Tyrosine Kinase ROR1 by Anti-ROR1 Monoclonal Antibodies and siRNA Induced Apoptosis of Melanoma Cells

The receptor tyrosine kinase (RTK) ROR1 is overexpressed and of importance for the survival of various malignancies, including lung adenocarcinoma, breast cancer and chronic lymphocytic leukemia (CLL). There is limited information however on ROR1 in melanoma. In the present study we analysed in seve...

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Bibliographic Details
Main Authors: Hojjat-Farsangi, Mohammad, Ghaemimanesh, Fatemeh, Daneshmanesh, Amir Hossein, Bayat, Ali-Ahmad, Mahmoudian, Jafar, Jeddi-Tehrani, Mahmood, Rabbani, Hodjatallah, Mellstedt, Hakan
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620154/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620154/

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