Rare Though Not Mutually Exclusive: A Report of Three Cases of Concomitant KRAS and BRAF Mutation and a Review of the Literature
KRAS mutations occur frequently in colorectal cancers (CRC) and predict lack of response to anti-epidermal growth factor receptor (EGFR) monoclonal antibody therapy. CRC BRAF mutations, most commonly at V600E, occur less than 10% of the time, and occur usually in KRAS wild-type tumors, and more freq...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Ivyspring International Publisher
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619093/ |