Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels

In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe malaria resulting in high rates of pediatric morbidity and mortality in these r...

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Bibliographic Details
Main Authors: Okeyo, Winnie A, Munde, Elly O, Okumu, Wilson, Raballah, Evans, Anyona, Samuel B, Vulule, John M, Ong’echa, John M, Perkins, Douglas J, Ouma, Collins
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618200/